Analytical Biochemistry Services Offered

If you have any questions about the services offered or a custom-designed chemical analysis, please contact:
Adrian Franke, PhD at This email address is being protected from spambots. You need JavaScript enabled to view it. or (808) 586-3008.

Targeted Analyses

  1. 1-hydroxy-pyrene in urine
  2. 5-Nitro-gamma tocopherol in plasma
  3. Acids (citrate cycle analytes): lactic acid, pyruvic acid, alpha-ketoglutaric acid, from liver tissue
  4. Aldehydes (formaldehyde, acetaldehyde, acrolein) by LCMS
  5. Alkaloids from urine, saliva, hair, plants by LCMS (see nicotine, cotinine, Areca alkaloids)
  6. Alkylresercinols from serum
  7. Ammonia in urine
  8. APO-A1 in plasma by AA
  9. Apo-B in plasma by AA
  10. Apo-E in plasma by AA
  11. Areca (Betel) alkaloids from urine, saliva, buccal cells, scalp hair, and plant materials by LCMS (arecoline, arecaidine, guvacine, guvacoline)
  12. Bisphenol-A in urine by LC/MSMS
  13. Caffeine and its metabolites in urine
  14. Calcium in plasma by AA
  15. Carotenoids in the eye by macular pigment optical density reading using heterochromatic flicker spectrophotometry
  16. Carotenoids including their isomers in plasma by HPLC/PDA (luteins, zeaxanthins, alpha- and beta-cryptoxanthins, lycopenes, alpha- and beta-carotenes)
  17. Chavibetol from urine, saliva, plants by LCMS
  18. Cholesterol (total) in plasma by AA
  19. Cholic acid, chenodeoxycholic acid, deoxycholic acid, lithocholic acid, ursodeoxycholic acid, and hyodeoxycholid acid from serum
  20. Choline, betaine, carnitine, trimethylamine-N-oxide from plasma or serum (TMAO) by LCMS
  21. Choline, betaine, CDP-choline, phosphocholine, glycerophosphocholine from liver tissue
  22. Citric acid, and the most abundant fatty acids from liver tissue
  23. Coenzyme Q10 (ubiquinol-10 and ubiquinone-10) by HPLC/PDA
  24. Cotinine and hydroxycotinine from saliva;
  25. Hydroxylated cholesterols in plasma by LCMS
  26. Coenzyme Q10 in plasma by HPLC/ECD (oxidized, reduced and total Q10)
  27. Creatinine in urine by AA
  28. CRP in plasma by AA
  29. DNA by HPLC
  30. DNA methylation, global (5-methyl-dC/dG)
  31. Fatty acids in plasma or RBC's by high-accuracy LCMS (myristic acid [MA, C14:0], stearic acid [SA, C18:0], palmitic acid [PA, C16:0], oleic acid [OA, C18:1], palmitoleic acid [PLA, C16:1], docosapentaenoic acid [DPA, C22:5 n-3], docosahexaenoic acid [DHA, C22:6 n-3], eicosapentaenoic acid [EPA, C20:5 n-3], α-linolenic acid [ALA, C18:3 n-3], eicosadienoic acid [EDA, C20:2 n-6], linoleic acid [LA, C18:2 n-6], arachidonic acid [AA, C20:4 n-6], α-eleostearic acid [αESA, C18:3]; stearic acid-d3 [SA-d3], linoleic acid-d4 [LA-d4], arachidonic acid-d8 [AA-d8], palmitoleic acid-d14 [PLA-d14], Eicosapentaenoic acid-d5 [EPA-d5], docosahexaenoic acid-d5 [DHA-d5], or any other fatty acid)
  32. Folates in plasma by LC/MSMS
  33. Glyphosate (Roundup), glufosinate and AMPA from urine by LCMS
  34. Haptoglobin in plasma by AA
  35. HDL-cholesterol in plasma by AA
  36. Homocysteine, cysteine in plasma by LCMS
  37. Hydroxylated cholesterols in plasma by LCMS
  38. Isoflavonoids, flavonoids, lignans, anthocyanins or other groups of phenolic agents from plasma, urine, breast milk, foods by LC/MSMS
  39. Isothiocyanates (ITC) from plasma or serum by LCMS (allyl-ITC, butenyl-ITC, phenethyl-ITC, iberin, sulforaphane)
  40. L-alanine, L-glutamic acid, L-glutamine, glucose-6-phosphate from liver tissue
  41. Lipid panel in plasma by AA (Chol, HDLC, triglycerides)
  42. Lipid-Phase Micronutrients in plasma or foods by HPLC/PDA/FD (12 carotenoids, 2 retinoids, 3 tocopherols)
  43. Macular pigment optical density by heterochromatic flicker spectrophotometry (using a model Macular Metrix II from Macular Metrics)
  44. Methylmalonic acid in plasma by LC/MSMS
  45. Neurotransmitters in CSF or plasma/serum by HPLC/FD/ECD: norepinephrine, 5-hydroxyindole-3-acetic acid, homovanillic acid, kynurenic acid, L-kynurenine, tryptophane
  46. Nicotine and metabolites from urine, saliva, hair, plants by LCMS (nicotine, nornicotine, anabasine, myosmine, cotinine, hydroxycotinine, NNN [N-nitrosonornicotine], NNK [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone], NAB [N-nitrosoanabasine], and NAT [N-nitrosoanatabine])
  47. Nitrogen, urea in urine by AA
  48. Oxytocin from serum by LCMS
  49. Parabens from urine by LCMS
  50. Phenoxyacetic acids (2,4-D; 2,4-T) from urine by LCMS
  51. Phospholipids (the most abundant arrays of phosphatidylcholines, phosphatidylethanolamines, sphingomyelins, lysophosphatidylcholines, and phosphatidylinositols) from liver tissue
  52. Phthalates in urine by LC/MSMS (phthalate, monoethyl phthalate, mono-n-butyl phthalate, mono-isobutyl phthalate, monobenzyl phthalate, mono(2-ethylhexyl) phthalate, mono(2-ethyl-5-hydroxyhexyl) phthalate, mono(2-ethyl-5-oxohexyl) phthalate, mono(2-ethyl-5-carboxypentyl) phthalate)
  53. Red blood cell preparation
  54. Roundup (glyphosate) and aminomethyl phosphonic acid (AMPA) from urine by LCMS
  55. Sucrose, fructose, glucose in urine by LC/MSMS
  56. Total phenol levels in food, urine, plasma
  57. Triclosan from urine by LCMS
  58. Triglycerides in plasma by AA**
  59. Trimethylamino-N-oxide (TMAO), choline, betaine, and carnithine from serum
  60. Vanillin from e-cigarette juices by LCMS
  61. Vitamin A and pro-vitamin A in plasma by HPLC/PDA
  62. Vitamin B group in plasma by LC/MS (pyridoxic acid, pyridoxal phosphate; folate, 5-methyltetrahydrofolate; methylmalonic acid; homocysteine, cysteine; choline, betaine)
  63. Vitamin C in plasma, food by HPLC/ECD or PDA
  64. Vitamin D in plasma by LC/MSMS (vitamin D2, vitamin D3, 25-hydroxy-vitamin D2, and 25-hydroxy-vitamin D3)
  65. Vitamin E in plasma by NP-HPLC/PDA/FD (all tocopherols)
  66. Vitamin K by LC/MSMS
  67. Vitamin and antioxidant panel (lipid soluble) from plasma by single HPLC/PDA/FD (25-hydroxy-vitamin D2 and 25-hydroxy-vitamin D3; alpha-, beta-, gamma-, and delta-tocopherol; all-trans and geometric isomers of lutein, zeaxanthin, alpha- and beta-cryptoxanthin, lycopene, and alpha- and beta-carotene; retinol and retinyl palmitate; ubiquinol-10 and ubiquinone-10)
  68. Steroids in urine and plasma/serum by LC/MS (estriol [E3], 16-epiestriol [16epi-E3], 17-epiestriol [17epi-E3], 16-ketoestradiol [16keto-E2], 16-α-hydroxyestrone [16αOH-E1], 2-methoxyestrone [2MeO-E1], 3-methoxyestrone [3Me-OE1], 4-methoxyestrone [4MeO-E1], 2-methoxyestradiol [2MeO-E2], 4-methoxyestradiol [4MeO-E2], 2-hydroxyestrone [2OH-E1], 4-hydroxyestrone [4OH-E1], 2-hydroxyestradiol [2OH-E2], progesterone [P], testosterone [T]), corticoids (cortisol, cortisone, etc.) and other steroids
  69. Any other assay based on clinical autoanalyzer technique (Pentra C400; Horiba)