Analytical Biochemistry Services Offered

If you have any questions about the services offered or a custom-designed chemical analysis, please contact:
Adrian Franke, PhD at This email address is being protected from spambots. You need JavaScript enabled to view it. or (808) 586-3008.

Analysis

1. 1-hydroxy-pyrene in urine
2. 5-Nitro-gamma tocopherol in plasma
3. Acids (citrate cycle analytes): lactic acid, pyruvic acid, alpha-ketoglutaric acid, from liver tissue
4. Aldehydes (formaldehyde, acetaldehyde, acrolein) by LCMS
5. Alkaloids from urine, saliva, hair, plants by LCMS (see nicotine, cotinine, Areca alkaloids)
6. Alkylresercinols from serum
7. Ammonia in urine
8. APO-A1 in plasma by AA
9. Apo-B in plasma by AA
10. Apo-E in plasma by AA
11. Areca (Betel) alkaloids from urine, saliva, buccal cells, scalp hair, and plant materials by LCMS (arecoline, arecaidine, guvacine, guvacoline)
12. Bisphenol-A in urine by LC/MSMS
13. Caffeine and its metabolites in urine
14. Calcium in plasma by AA
15. Carotenoids in the eye by macular pigment optical density reading using heterochromatic flicker spectrophotometry
16. Carotenoids including their isomers in plasma by HPLC/PDA (luteins, zeaxanthins, alpha- and beta-cryptoxanthins, lycopenes, alpha- and beta-carotenes)
17. Chavibetol from urine, saliva, plants by LCMS
18. Cholesterol (total) in plasma by AA
19. Cholic acid, chenodeoxycholic acid, deoxycholic acid, lithocholic acid, ursodeoxycholic acid, and hyodeoxycholid acid from serum
20. Choline, betaine, carnitine, trimethylamine-N-oxide from plasma or serum (TMAO) by LCMS
21. Choline, betaine, CDP-choline, phosphocholine, glycerophosphocholine from liver tissue
22. Citric acid, and the most abundant fatty acids from liver tissue
23. Coenzyme Q10 (ubiquinol-10 and ubiquinone-10) by HPLC/PDA
24. Cotinine and hydroxycotinine from saliva;
25. Hydroxylated cholesterols in plasma by LCMS
26. Coenzyme Q10 in plasma by HPLC/ECD (oxidized, reduced and total Q10)
27. Creatinine in urine by AA
28. CRP in plasma by AA
29. DNA by HPLC
30. DNA methylation, global (5-methyl-dC/dG)
31. Fatty acids in plasma or RBC's by high-accuracy LCMS (myristic acid [MA, C14:0], stearic acid [SA, C18:0], palmitic acid [PA, C16:0], oleic acid [OA, C18:1], palmitoleic acid [PLA, C16:1], docosapentaenoic acid [DPA, C22:5 n-3], docosahexaenoic acid [DHA, C22:6 n-3], eicosapentaenoic acid [EPA, C20:5 n-3], α-linolenic acid [ALA, C18:3 n-3], eicosadienoic acid [EDA, C20:2 n-6], linoleic acid [LA, C18:2 n-6], arachidonic acid [AA, C20:4 n-6], α-eleostearic acid [αESA, C18:3]; stearic acid-d3 [SA-d3], linoleic acid-d4 [LA-d4], arachidonic acid-d8 [AA-d8], palmitoleic acid-d14 [PLA-d14], Eicosapentaenoic acid-d5 [EPA-d5], docosahexaenoic acid-d5 [DHA-d5], or any other fatty acid)
32. Folates in plasma by LC/MSMS
33. Glyphosate (Roundup), glufosinate and AMPA from urine by LCMS
34. Haptoglobin in plasma by AA
35. HDL-cholesterol in plasma by AA
36. Homocysteine, cysteine in plasma by LCMS
37. Hydroxylated cholesterols in plasma by LCMS
38. Isoflavonoids, flavonoids, lignans, anthocyanins or other groups of phenolic agents from plasma, urine, breast milk, foods by LC/MSMS
39. Isothiocyanates (ITC) from plasma or serum by LCMS (allyl-ITC, butenyl-ITC, phenethyl-ITC, iberin, sulforaphane)
40. L-alanine, L-glutamic acid, L-glutamine, glucose-6-phosphate from liver tissue
41. Lipid panel in plasma by AA (Chol, HDLC, triglycerides)
42. Lipid-Phase Micronutrients in plasma or foods by HPLC/PDA/FD (12 carotenoids, 2 retinoids, 3 tocopherols)
43. Macular pigment optical density by heterochromatic flicker spectrophotometry (using a model Macular Metrix II from Macular Metrics)
44. Metabolomics by LCMS
45. Methylmalonic acid in plasma by LC/MSMS
46. Neurotransmitters in CSF or plasma/serum by HPLC/FD/ECD: norepinephrine, 5-hydroxyindole-3-acetic acid, homovanillic acid, kynurenic acid, L-kynurenine, tryptophane
47. Nicotine and metabolites from urine, saliva, hair, plants by LCMS (nicotine, nornicotine, anabasine, myosmine, cotinine, hydroxycotinine, NNN [N-nitrosonornicotine], NNK [4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone], NAB [N-nitrosoanabasine], and NAT [N-nitrosoanatabine])
48. Nitrogen, urea in urine by AA
49. Oxytocin from serum by LCMS
50. Parabens from urine by LCMS
51. Phenoxyacetic acids (2,4-D; 2,4-T) from urine by LCMS
52. Phospholipids (the most abundant arrays of phosphatidylcholines, phosphatidylethanolamines, sphingomyelins, lysophosphatidylcholines, and phosphatidylinositols) from liver tissue
53. Phthalates in urine by LC/MSMS (phthalate, monoethyl phthalate, mono-n-butyl phthalate, mono-isobutyl phthalate, monobenzyl phthalate, mono(2-ethylhexyl) phthalate, mono(2-ethyl-5-hydroxyhexyl) phthalate, mono(2-ethyl-5-oxohexyl) phthalate, mono(2-ethyl-5-carboxypentyl) phthalate)
54. Red blood cell preparation
55. Roundup (glyphosate) and aminomethyl phosphonic acid (AMPA) from urine by LCMS
56. Sucrose, fructose, glucose in urine by LC/MSMS
57. Total phenol levels in food, urine, plasma
58. Triclosan from urine by LCMS
59. Triglycerides in plasma by AA**
60. Trimethylamino-N-oxide (TMAO), choline, betaine, and carnithine from serum
61. Vanillin from e-cigarette juices by LCMS
62. Vitamin A and pro-vitamin A in plasma by HPLC/PDA
63. Vitamin B group in plasma by LC/MS (pyridoxic acid, pyridoxal phosphate; folate, 5-methyltetrahydrofolate; methylmalonic acid; homocysteine, cysteine; choline, betaine)
64. Vitamin C in plasma, food by HPLC/ECD or PDA
65. Vitamin D in plasma by LC/MSMS (vitamin D2, vitamin D3, 25-hydroxy-vitamin D2, and 25-hydroxy-vitamin D3)
66. Vitamin E in plasma by NP-HPLC/PDA/FD (all tocopherols)
67. Vitamin K by LC/MSMS
68. Vitamin and antioxidant panel (lipid soluble) from plasma by single HPLC/PDA/FD (25-hydroxy-vitamin D2 and 25-hydroxy-vitamin D3; alpha-, beta-, gamma-, and delta-tocopherol; all-trans and geometric isomers of lutein, zeaxanthin, alpha- and beta-cryptoxanthin, lycopene, and alpha- and beta-carotene; retinol and retinyl palmitate; ubiquinol-10 and ubiquinone-10)
69. Steroids in urine and plasma/serum by LC/MS (estriol [E3], 16-epiestriol [16epi-E3], 17-epiestriol [17epi-E3], 16-ketoestradiol [16keto-E2], 16-α-hydroxyestrone [16αOH-E1], 2-methoxyestrone [2MeO-E1], 3-methoxyestrone [3Me-OE1], 4-methoxyestrone [4MeO-E1], 2-methoxyestradiol [2MeO-E2], 4-methoxyestradiol [4MeO-E2], 2-hydroxyestrone [2OH-E1], 4-hydroxyestrone [4OH-E1], 2-hydroxyestradiol [2OH-E2], progesterone [P], testosterone [T]), corticoids (cortisol, cortisone, etc.) and other steroids
70. Any other assay based on clinical autoanalyzer technique (Cobas MiraPlus CC)